m6A(N6-甲基腺苷)是哺乳动物 mRNA 中丰富的内部修饰。这种修饰由 m6A 甲基转移酶或称 “写手"(如 METTL3 和 METTL14)完成,并可由作为 “擦除器 "的去甲基化酶(如 FTO 和 ALKBH5)逆转。m6A 修饰的 mRNA 的稳定性受 m6A 阅读蛋白 YTHDFs 的调节,YTHDFs 可识别 m6A 并降低目标转录本的稳定性。
targets m6A in WB, IHC, IF, IP, RIP, Dot Blot, ELISA applications and shows reactivity with m6A, Human, Mouse, Rat samples.
Tested Applications | RIP, IHC, ELISA, Dot Blot Application Description |
Cited Applications | WB, IHC, IF, IP, RIP |
Tested Reactivity | m6A, Human, Mouse, Rat |
Cited Reactivity | human, mouse, rat, pig, monkey |
Immunogen | Compound |
Host / Isotype | Mouse / IgG3 |
Class | Monoclonal |
Type | Antibody |
Full Name | m6A |
Synonyms | 6-N-Methyladenoside, m6A, N6-methyladenosine |
GenBank Accession Number | m6A |
Gene Symbol | |
Gene ID (NCBI) | |
RRID | AB_2918796 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
货号 | 品名 | 规格 | 品牌 |
78DA10019 | m6A Monoclonal antibody | 50 µL | BIOHUB |